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Endocrine Abstracts

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ea0086ec1.2 | Early Career Prize Lecture Clinical | SFEBES2022

Central adiposity raises serum calcium concentrations and increases risk of kidney stone disease

Lovegrove Catherine , Besevic Jelena , Wiberg Akira , Lacey Ben , Littlejohns Thomas , Allen Naomi , Goldsworthy Michelle , Kim Jihye , Hannan Fadil , Curhan Gary , Turney Ben , McCarthy Mark , Mahajan Anubja , Thakker Rajesh , Holmes Michael , Furniss Dominic , Howles Sarah

Background: Kidney stone disease (KSD) has been linked to obesity, metabolic syndrome and higher serum calcium concentration (SCa). The mechanisms underlying these associations are uncertain. Using conventional and genetic epidemiological techniques, we aimed to investigate the effects of adiposity on KSD.Methods: Observational associations between adiposity and incident KSD in 479, 405 people from the UK Biobank were assessed. Genome-wide association st...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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